2-Buten-1-one, 3-(dimethylamino)-1-(2-thienyl)-
3-(Dimethylamino)-1-(2-thienyl)-2-buten-1-one
CAS: 112677-16-4
Molecular Formula: C10H13NOS
2-Buten-1-one, 3-(dimethylamino)-1-(2-thienyl)- - Names and Identifiers
2-Buten-1-one, 3-(dimethylamino)-1-(2-thienyl)- - Physico-chemical Properties
| Molecular Formula | C10H13NOS |
| Molar Mass | 195.28 |
| Density | 1.102±0.06 g/cm3(Predicted) |
| Melting Point | 94-96°C |
| Boling Point | 281.7±36.0 °C(Predicted) |
| pKa | 5.60±0.70(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD03791167 |
2-Buten-1-one, 3-(dimethylamino)-1-(2-thienyl)- - Risk and Safety
| Hazard Class | IRRITANT |
2-Buten-1-one, 3-(dimethylamino)-1-(2-thienyl)- - Introduction
3-(Dimethylamino)-1-(2-thienyl)-2-buten-1-one is an organic compound whose chemical formula is C12H15NOS.
The compound mainly has the following properties:
1. Appearance: 3-(Dimethylamino)-1-(2-thienyl)-2-buten-1-one is a yellow to orange solid.
2. Solubility: It has good solubility in solvents, low solubility in water, soluble in organic solvents such as ethanol, acetone, etc.
3. Melting point: The melting point of the compound is in the range of 80-82°C.
4. chemical properties: 3-(Dimethylamino)-1-(2-thienyl)-2-buten-1-one is a reactive compound that can react with other chemical substances.
This compound has a wide range of applications in some important fields, including organic synthesis and medicine. Its uses are as follows:
1. organic synthesis: 3-(Dimethylamino)-1-(2-thienyl)-2-buten-1-one can be used as a fluorescent dye, raw material of substituted carboxylic acid methyl ester, and can also be used in the synthesis of organic photoelectric materials.
2. Pharmaceutical field: The compound is widely used in drug research and development, for example, for the synthesis of biologically active compounds.
regarding the method of preparing 3-(Dimethylamino)-1-(2-thienyl)-2-buten-1-one, the specific synthetic route may have various schemes, but the commonly used methods mainly include the following steps:
1. synthesis of 2-thioacetophenone (2-Thienyl-2-propen-1-one): by 2-butyl ketone and sodium sulfide reaction system.
2. Synthesis of 3-(dimethylamino)-1-(2-thiophenyl)-2-propanone (3-(Dimethylamino)-1-(2-thienyl)-2-propanone): Reaction of 2-thioacetophenone with dimethylamine.
3. Synthesis of 3-(Dimethylamino)-1-(2-thienyl)-2-buten-1-one: 3-(dimethylamino)-1-(2-thiophenyl)-2-propanone is converted into the target product by reduction reaction.
When using 3-(Dimethylamino)-1-(2-thienyl)-2-buten-1-one, you need to pay attention to the following safety information:
1. This compound is irritating and toxic. It should be operated in a closed and ventilated place to avoid inhalation and contact with skin.
2. During handling and storage, protective measures should be taken, such as appropriate protective gloves, glasses and protective clothing.
3. Avoid contact with oxidizing agents to avoid dangerous reactions.
4. Waste shall be disposed of in accordance with local regulations.
The compound mainly has the following properties:
1. Appearance: 3-(Dimethylamino)-1-(2-thienyl)-2-buten-1-one is a yellow to orange solid.
2. Solubility: It has good solubility in solvents, low solubility in water, soluble in organic solvents such as ethanol, acetone, etc.
3. Melting point: The melting point of the compound is in the range of 80-82°C.
4. chemical properties: 3-(Dimethylamino)-1-(2-thienyl)-2-buten-1-one is a reactive compound that can react with other chemical substances.
This compound has a wide range of applications in some important fields, including organic synthesis and medicine. Its uses are as follows:
1. organic synthesis: 3-(Dimethylamino)-1-(2-thienyl)-2-buten-1-one can be used as a fluorescent dye, raw material of substituted carboxylic acid methyl ester, and can also be used in the synthesis of organic photoelectric materials.
2. Pharmaceutical field: The compound is widely used in drug research and development, for example, for the synthesis of biologically active compounds.
regarding the method of preparing 3-(Dimethylamino)-1-(2-thienyl)-2-buten-1-one, the specific synthetic route may have various schemes, but the commonly used methods mainly include the following steps:
1. synthesis of 2-thioacetophenone (2-Thienyl-2-propen-1-one): by 2-butyl ketone and sodium sulfide reaction system.
2. Synthesis of 3-(dimethylamino)-1-(2-thiophenyl)-2-propanone (3-(Dimethylamino)-1-(2-thienyl)-2-propanone): Reaction of 2-thioacetophenone with dimethylamine.
3. Synthesis of 3-(Dimethylamino)-1-(2-thienyl)-2-buten-1-one: 3-(dimethylamino)-1-(2-thiophenyl)-2-propanone is converted into the target product by reduction reaction.
When using 3-(Dimethylamino)-1-(2-thienyl)-2-buten-1-one, you need to pay attention to the following safety information:
1. This compound is irritating and toxic. It should be operated in a closed and ventilated place to avoid inhalation and contact with skin.
2. During handling and storage, protective measures should be taken, such as appropriate protective gloves, glasses and protective clothing.
3. Avoid contact with oxidizing agents to avoid dangerous reactions.
4. Waste shall be disposed of in accordance with local regulations.
Last Update：2024-04-09 21:54:55
